Highly active antiretroviral therapy (HAART) as standard of care has changed the natural history of HIV infection into a controllable chronic disease requiring long-term antiretroviral (ARV) treatment. In the HIV infection setting, antiretroviral treatment is characterized by differing rates of responses and adverse events. Numerous studies report that the administration of standard doses of most antiretroviral drugs results in significant variations in plasma drug concentrations among different individuals, influencing antiviral activity as well as incidence of drug-related toxicities.
Last date updated on March, 2025