Stomach cancer and esophageal cancer are among the most common and lethal cancers worldwide, causing 934 000 and 380 000
deaths each year respectively and a substantial amount of deaths occurs in less-developed countries . Similarly, they cause high burden in
China in terms of incidence and mortality. According to the latest data of Chinese cancer registry, esophageal cancer is the fifth of the
10 most common cancers and stomach cancer is the second, and with respect to mortality, they rank the forth and third of 10 leading cancers
respectively. Progress has been achieved in the field of prevention, diagnosis, and treatment of esophageal cancer and stomach cancer, and
also obvious variations have been revealed in cancer patterns during the last few decades. According to the study on cancer death survey in Chinese
population covering the population of 850 million during 1973 and 1975, cancers of stomach and esophagus were the top two causes of
cancer death in China accounting for 23.03% and 21.80% of all caner caused deaths. The age-standardized mortality rate by world population
(ASMR) were 23.86/105 , a high level in the world and 23.40/105 , the highest level in the world, respectively. The geographic distribution
revealed exceptional high-risk areas of stomach cancer like Changle and Linqu, esophageal cancer like Linzhou and Cixian, which attract
the attention of scholars and researchers all over the world.
Last date updated on March, 2025