Journal of Cellular and Molecular Pharmacology
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Biotransformation
Biotransformation is the process by which living organisms, particularly enzymes in the liver, chemically alter substances, including drugs, toxins, and endogenous compounds.
This transformation typically involves converting lipophilic compounds into more hydrophilic metabolites to facilitate their excretion from the body. Biotransformation encompasses two main phases: Phase I reactions and Phase II reactions.