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Cell signaling and activation

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Cell signaling and activation

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Cell signaling and activation

Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. Cell activation is the response towards the incoming cell signal by bringing change in biochemical reactions.

Related Journals of Cell signaling
Journal of Molecular Immunology, Cell Signaling 黑料网, Cell & Developmental Biology Open Access, Cell Biology: Research & Therapy Hybrid 黑料网, Cell Biology: Research & Therapy Hybrid 黑料网, Journal of Molecular Signaling, Journal of Cell Communication and Signaling, Journal - Cell signalling and Trafficking (黑料网), Inflammation and Cell Signaling

Cell signaling and activation

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    A novel synthetic antimicrobial peptide for the cure of gram-negative infections: Mechanism of action, efficacy in vivo, toxicity, bio-distribution and resistance selection
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    Investigation and molecular typing of Brucella isolated from dairy cattle herd immunized with Brucella abortus RB51 vaccine in Egypt
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    Effect of ciprofloxacin and levofloxacin alone or in combination with N-acetylcysteine on biofilm-producing Enterococcus faecalis: Contaminated root canals of extracted human teeth
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    Diagnosed, Identified, Current and Complete Depression Among Patients Attending Primary Care in Southern Catalonia: Different Aspects of the Same Concept
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    Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation
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    To compare serum leptin levels in obese women with polycystic ovary syndrome (PCOS) and normal ovulatory obese subjects in Saudi Arabia, and to evaluate the interrelationship between leptin concentration, sex hormones, and insulin resistance.
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  • Wang Bin
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    Classically, the 3脙垄芒聜卢芒聞垄untranslated region (3脙垄芒聜卢芒聞垄UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3脙垄芒聜卢芒聞垄UTR alone, without all other elements in mRNA such as 5脙垄芒聜卢芒聞垄UTR and coding region. The importance of independent 3脙垄芒聜卢芒聞垄UTR RNA (referred as I3脙垄芒聜卢芒聞垄UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3脙垄芒聜卢芒聞垄UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3脙垄芒聜卢芒聞垄UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3脙垄芒聜卢芒聞垄UTR were important for its tumor suppression activity. Then, the C/EBP 3脙垄芒聜卢芒聞垄UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3脙垄芒聜卢芒聞垄UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3脙垄芒聜卢芒聞垄UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990脙垄芒聜卢芒聞垄s to 2000脙垄芒聜卢芒聞垄s, world scientists found several 3脙垄芒聜卢芒聞垄UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3脙垄芒聜卢芒聞垄UTR regions, although the existence of their transcribed products as independent 3脙垄芒聜卢芒聞垄UTR RNAs is still to be confirmed. Our studies indicate that the independent 3脙垄芒聜卢芒聞垄UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
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  • Lu Jia
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  • Yang Rongfei
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  • Gregory K. Watkins
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    Determinants of HIV transmission and sexual risk practices among women of childbearing age in semi-urban communities of Rivers State, Nigeria
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    Production of rosmarinic acid from in-vitro culture of Basil (Ocimum basilicum L) and lemon balm (Melissa officinalis L)
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    Sugar-modified PPI dendrimers as carriers of anti-leukemia drugs
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    New Tools to Study and Perturb the Glycocalyx
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    Accelerating influenza research; Vaccines, antivirals, immunodulators and monoclonal antibodies. The manufacture of a new H3N2 virus for the human viral challenge model
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  • Eda Yasar
    The effect of music on the comfort and anx脙聞脗卤ety of the elderly l脙聞脗卤v脙聞脗卤ng nurs脙聞脗卤ng home
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  • Marisa Krairiksh
    Implementation of Nursing Service Strategies Supporting ASEAN Economic Community in the Year 2015 of Nursing Organizations in Thailand
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  • John D Sullivan
    Creating an oligopoly in the treatment of end stage renal disease and the subsequent impact on home hemodialysis therapies
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  • Joseph R Purita
    The use of supplements and cytokines in platelet rich plasma injections and stem cell treatments
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  • Adel Nefzi
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    Design of small synthetic molecules that mimic IL-4 binding to IL-4R脙聨脗卤, which therefore promotes alternate macrophage differentiation (M2) with minimal effect on the endothelial and vascular IL-4R脙聨脗卤.
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    Myocardial TRPM7 channels: Biophysical properties and involvement in cardiac diseases
    | PDF Version
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    Design and Development Of a Knowledge driven Web Based Remote Cardio Patient Data Monitoring and Diagnostic Tool
    | PDF Version
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    Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol induced myocardial infarction in rats
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  • Pollen K F Yeung
    ATP Metabolism as Biomarker Target for Cardiovascular Protection and Toxicity
    | PDF Version
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    Spontaneous Ventricular Arrhythmias in Early Clinical Trials A Report from a Single and Repeated Ascending Dose Study
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    Design, synthesis and antidiabetic, cardiomyopathy studies of cinnamic acid-amino acid hybrid analogs
    | PDF Version
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    Novel sildenafil analogues: possible drugs for increased sensitivity to chemotherapeutic agents
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  • Praveen Thaggikuppe Krishnamurthy
    Newer approaches to the discovery of glitazones
    | PDF Version
  • Alexander D. Verin
    Extracellular purines in vascular endothelial barrier preservation
    | PDF Version
  • Robert M. Mentzer, Jr.
    The homeostatic intracellular repair response (HIR2) and autophagy during cardiac surgery
    | PDF Version
  • Janardhana Rao Babburi
    An unusual case of LV Myxoma extending through Aortic Valve presented with Antero Septal Myocardial Infarction
    | PDF Version
  • Norbert Jost
    Atrial remodelling in permanent atrial fibrillation. Mechanism and implications
    | PDF Version
  • Maravic Stojkovic V
    Blood Loss and Intraoperative Salvage Procedure in Patients Underwent Re-operation Coronary Artery Bypass
    | PDF Version
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    Ion channels phosphorylopathy: 3rd International Conference on Clinical & Experimental Cardiology April 15-17, 2013 A link between genomic variations and heart arrhythmia
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