Journal of Autacoids and Hormones
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Racemic Epinephrine
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Racemic Epinephrine
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Racemic Epinephrine
Racemic epinephrine is a racemic mixture of epinephrine and is a sympathomimetic bronchodilator that is delivered by aerosol. Commonly used in croup (laryngotracheobronchitis) and when stridor is present after removal of an endotracheal tube (extubation). Racemic epinephrine prepared for aerosolization is equivalent to a 1:100 dose of epinephrine. The term racemic epinephrine refers to a mixture of 50 % each of the dextro-rotatory and levo-rotatory isomers. The l-isomer [(R)-epinephrine] is present in the adrenal glands of animals and humans and is produced commercially by extraction from animal glands or by separation of the d- and l-isomers in the synthetic preparation.
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