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ISSN: 2476-2253

Journal of Cancer Diagnosis
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Thyroid Cancer Diagnosis

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Thyroid Cancer Diagnosis

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Thyroid Cancer Diagnosis

Thyroid Cancer can be diagnosed by Physical exam for diagnosing of goiter and tumour. Blood tests: It is done for checking thyroid hormone levels. Fine-needle biopsy. Imaging tests: MRI, PET, CT scan. Genetic testing for diagnosing medullary thyroid cancer.

 Related Journals of Thyroid Cancer Diagnosis
Journal of Cancer Diagnosis,Cancer Case Reports Journal,Cancer Prevention Journal,Cancer Medicine Journal,Thyroid : official journal of the American Thyroid Association,Journal of Thyroid Research, Cancer Science, Cancer Prevention Research.

Thyroid Cancer Diagnosis

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    The role of tissue-specific type 2 5’-deiodinase enzyme activities in Graves’ orbitopathy and systemic sclerosis: a new candidate in thyroid autoimmunity
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    Radio-immunotherapy of cancer: Therapeutic efficacy, underlying mechanisms and potential applications
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  • Yosef Yarden
    Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
    | PDF Version
  • Fan-Gang Tseng
    Fan-Gang-Tseng-National-Tsing-Hua-University-Taiwan-Nano-Micro-fluidic-systems-for-circulating-Tumor-Cells-(CTCs)-rapid-detection-and-diagnosis
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    Survivin siRNA nano particles are capable of inhibiting liver cancer cell growth both in vitro and in vivo
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    Mechanisms of Early Pregnancy-Mediated Breast Cancer Protection
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    Breast cancer: A comparison among different diagnostic and therapeutic protocols
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    Diagnostic biomarkers in metastatic breast cancer
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    Illitracy and Breast Cancer Screening Utilization: A Case Study of Saudi Women over 60 Years of Age
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    PEGylated-thymoquinone-nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a
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    Prognostic value of ER, PR, and HER2 breast cancer biomarkers and AJCC’s TNM staging system on overall survival of Caucasian females with breast cancer: An institution’s 10 year experience
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    Cancer immunotherapy utilizing gene-modified T cells: from the bench to the clinic.
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    HER-2/neu as a target forListeria-based cancer immunotherapy for breast cancer
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    FSIP1: A new potential early screening marker for breast cancer
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    Screening of Breast Cancer from Mammography to MR Imaging
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    Resveratrol modulates expression of ABC transporters in non-small lung cancer cells: Molecular docking and gene expression studies
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    Engineered T cells: Next-generation cancer immunotherapy
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    Localized regulated expression of IL-12 as a gene therapy approach to cancer immunotherapy
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    Using VBIM technique to identify drug resistance genes in ovarian cancer
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    Characteristics of allergy in autoimmune thyroid diseases
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    Using DNA copy number aberrations in naturally occurring canine cancers to identify candidate drivers of carcinogenesis
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    Prenatal Diagnosis
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    Nanocolloidsfor Cancer
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    Meta-analysis of transcriptional profiles in cancer for prognosis prediction and metastatic gene identification
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    Double Targeting as an Effective Anti-Cancer Strategy
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    Gene expression profiling for targeted cancer treatment
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    Construction of cancer pathways for personalized medicine
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    Bacteria-mediated expression of cargo drugs and reporter gene for cancer-specific theranostics
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    A proteomic-bioinformatic integrated approach for studying the effect of a peptide drug candidate on ovarian Cancer
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    Translating multidimensional cancer omics data into biological insights
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