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ISSN: 2329-910X

Clinical Research on Foot & Ankle
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Bone Health in Foot

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Bone Health in Foot

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Bone Health in Foot

During the growing years, body needs calcium to build strong bones. The feet are flexible structures of bones, joints, muscles, and soft tissues that let us stand upright and perform activities like walking, running, and jumping. Stress fracture is a small crack in bone. Stress fracture usually occurs in the people who change their regular activities. The main cause of stress fractures is sudden increase in physical activity. Many other factors which cause stress fracture are bone insufficiency, improper technique, improper equipment.

Related Journals of Ankle Fracture

Foot and Ankle InternationalJournal of Foot and Ankle SurgeryFoot and Ankle ClinicsFoot and Ankle Surgery,Journal of Foot and Ankle Research, Foot and Ankle Specialist, Techniques in Foot and Ankle Surgery, Diabetic Foot and Ankle

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    The effect of body mass index on endometrial cancer: A meta-analysis
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    Pathways and genes under positive selection in metabolic diseases
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    Factors related with early treatment for malaria in the Brazilian Amazon: A multivariable approach using a ten-year population-based malaria surveillance database
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    Mental Health Consultation in Ontario’s Immigrant Populations
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    Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
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  • Ding-Gan Liu
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    Counterfeit MEDICINES A GLOBAL THREAT
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  • Fuat OKUMUÅž
    ¹ó³Ü²¹³Ù-°¿°­±«²Ñ±«ÃƒÂ…ž-³Ò±ð»å¾±³ú-±«²Ô¾±±¹±ð°ù²õ¾±³Ù²â-°Õ³Ü°ù°ì±ð²â-±õ²Ô±¹±ð²õ³Ù¾±²µ²¹³Ù¾±´Ç²Ô-´Ç´Ú-³Ù³ó±ð-±ð´Ú´Ú±ð³¦³Ù-´Ç´Ú-³Ù¾±´Ç2-´Ç²Ô-³Ù³ó±ð-³Ù³ó±ð°ù³¾²¹±ô-³¾±ð³¦³ó²¹²Ô¾±³¦²¹±ô-²¹²Ô»å-±ð°ù´Ç²õ¾±±¹±ð-±è°ù´Ç±è±ð°ù³Ù¾±±ð²õ-´Ç´Ú-²¹±¹¾±²¹³Ù¾±´Ç²Ô-³Ù³ó±ð°ù³¾´Ç±è±ô²¹²õ³Ù¾±³¦-³¦´Ç³¾±è´Ç²õ¾±³Ù±ð
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    The inflammasome: Critical roles in intestinal homeostasis
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  • Fawad Javed
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    Characterization and immunogenicity in mice of rececombinant influenza haemagglutinins produced in Leishmania tarentolae
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  • Vladimir Sulimov
    “Vladimir Sulimov-Dimonta-Ltd-and-Lomonosov-Moscow-State-University-Russia-is-it-possible-to-improve-considerably -the-accuracy-of-docking-programsâ€ÂÂ
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  • Young Chul Kim
    “Young Chul Kim-Seoul-National-University-Korea-Hepatoprotective-activity-of-silymarin-against-acetaminophen-involves-an-enhancement-of-the-glutathione-dependent-detoxification-capacityâ€ÂÂ
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  • Christain Dani
    Human Induced Pluripotent Stem cells: A new source for brown and white adipocytes
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  • Simin Fazelipour
    “Simin Fazelipour-Islamic-Azad-University-Tehran-Medical-Sciences-Branch-Tehran-Iran-evaluation-of-histopathologic-and-histomorphometric-changes-of-adrenal-gland-tissue-following-consumption-of-Methylphenidate-in-male-miceâ€ÂÂ
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  • Mai Ahmed
    “Mai Ahmed-university-of-Bath-UK-Identification-of-aconitine-artefact-in-alcoholic-extractsâ€ÂÂ
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  • Yung-Chih Kuo
    “Yung-Chih Kuo-National-Chung-Cheng-University-Republic-of-China-Targeting-delivery-of-etoposide-to-inhibit-the-growth-of-human-glioblastoma-multiforme-using-lactoferrin-and-folic-acid-grafted-poly(lactide-co-glycolide)-nanoparticlesâ€ÂÂ
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