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Cellular and Molecular Biology
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Cellular DNA Studies

Cellular DNA studies works with the function of the cellular DNA and its applications such as cell division. The morphological, molecular biology studies of the cellular DNA are analysed indepth in Cellular DNA studies. Cells contain the body’s hereditary material, the DNA. Most DNA is located in the cell nucleus (nuclear DNA), but a small amount of DNA can also be found in the mitochondria (mitochondrial DNA or mtDNA). An important property of DNA is that it can make copies of itself. Each strand of DNA in the double helix can serve as a template for duplicating the sequence of bases. This is important when cells divide as each new cell needs to have an exact copy of the DNA present in the old cell. Because the total length of cellular DNA in cells is up to a hundred thousand times the cell’s length, the packing of DNA into chromosomes is crucial to cell architecture. Histone protein helps the DNA to be packaged inside the cell. Bacterial chromosomes usually are circular DNA molecules that replicate from a single origin. The general structure of chromatin is remarkably similar in the cells of all eukaryotes including fungi, plants, and animals.

Related Journals of Cellular DNA Studies

Journal of Cell Science & Therapy, Cloning & Transgenesis, Journal of Genetic Syndromes & Gene Therapy, Transcriptomics: 黑料网, Hereditary Genetics: Current Research, Cell, Journal of Cell Biology, Molecular Cell, Journal of Cell Science, Journal of Cellular Physiology

 

Cellular DNA Studies

Expert PPTs

Speaker PPTs

  • Shuo Wang
    Childhood obesity interacts with the HIF3A variant on plasma ALT mediated by DNA methylation
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  • Eva E Avila
    Interaction of the parasite Trichomonas vaginalis with human neutrophil extracellular traps
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    Cathodoluminescence petrography for provenance studies of the sandstones of Ora Formation (Devonian-Carboniferous), Iraqi Kurdistan Region, Northern Iraq
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  • Mustafa M Hariri
    Importance of methods脙垄芒聜卢芒聞垄 selection in the geosciences studies and exploration
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  • Afsar Rahbar
    Studies of the importance of Cytomegalovirus infection in breast cancer
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  • Trung-Dinh Han
    Device-To-Device (D2D) Communication in 5G Cellular Networks
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  • Jim Polarine
    Case studies of human fl ora and spore contamination in clean rooms
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    Challenges in parenteral formulation development studies and an evaluation from QbD point of view
    | PDF Version
  • Jianfeng Hong
    Extractable and leachable studies of parenteral infusion and transfusion products
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  • Dongmei Li
    Dongmei Li- University-of-Rochester-An-evaluation-of-statistical-methods-for-DNA-methylation-microarray-data-analysis
    | PDF Version
  • Stephanie Ramos
    Enhanced Delivery of Dna-Based Vaccines and Immunotherapeutics through Next-Generation Electroporation Devices
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  • Fathia El Sharkawi
    The effect of PTEN and TRAIL genes loaded on nanoparticles on hepatocellular carcinoma
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  • Yosef Yarden
    Classically, the 3脙垄芒聜卢芒聞垄untranslated region (3脙垄芒聜卢芒聞垄UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3脙垄芒聜卢芒聞垄UTR alone, without all other elements in mRNA such as 5脙垄芒聜卢芒聞垄UTR and coding region. The importance of independent 3脙垄芒聜卢芒聞垄UTR RNA (referred as I3脙垄芒聜卢芒聞垄UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3脙垄芒聜卢芒聞垄UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3脙垄芒聜卢芒聞垄UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3脙垄芒聜卢芒聞垄UTR were important for its tumor suppression activity. Then, the C/EBP 3脙垄芒聜卢芒聞垄UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3脙垄芒聜卢芒聞垄UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3脙垄芒聜卢芒聞垄UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990脙垄芒聜卢芒聞垄s to 2000脙垄芒聜卢芒聞垄s, world scientists found several 3脙垄芒聜卢芒聞垄UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3脙垄芒聜卢芒聞垄UTR regions, although the existence of their transcribed products as independent 3脙垄芒聜卢芒聞垄UTR RNAs is still to be confirmed. Our studies indicate that the independent 3脙垄芒聜卢芒聞垄UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
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  • Arny L Blanchard
    Long-term environmental studies and stewardship in Alaska: A case study from Port Valdez
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    FISH SPECIES IDENTIFICATION AND BIODIVERSIFICATION IN ENUGU METROPOLIS RIVER BY DNA BARCODING
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  • Arshad mahmood
    TRANSPORT OF SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) ACROSS MUCUS AND CELLULAR INTERNALIZATION
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  • Mahmoud Balbaa
    CELLULAR AND MOLECULAR ACTIONS OF GROWTH FACTORS
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  • Konrad Sandhoff
    Lysosomal & extracellular degradation of GlcCer: Protein & lipid modifiers
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  • Soha M Hamdy
    Biochemical studies on the effect of turmeric on breast cancer of rats
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  • Adel Nefzi
    脙垄芒聜卢脜聯Adel Nefzi-Torrey-Pines-Institute-for-Molecular-Studies-USA-Diversity-Oriented-Synthesis-of-low-Molecular-Weight-Acyclic-and-Heterocyclic-Compounds-from-Resin-bound-Polyamides-Application-for-Drug-Discovery脙垄芒聜卢脗聺
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  • Dalia Hussein Soliman
    脙垄芒聜卢脜聯Dalia Hussein Soliman-Al-Azhar-University-Egypt-Design-synthesis-docking-and-QSAR-studies-of-novel-3-5-diaryl-pyrazole-derivatives-and-their-evaluation-as-antioxidants-and-as-Immunomodulators-inhibitors-of-TNF-脙聨脗卤-IL-2-IL-6脙垄芒聜卢脗聺
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  • Xiaomei Lu
    Ocean subsurface studies with the CALIPSO spaceborne lidar
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    Immunotoxicity of industrial effluents in fin fish: An alternative animal model for immunotoxicological studies
    | PDF Version
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    Ethnomedical studies of plants used for treatment of diseases in eastern part of Nigeria
    | PDF Version
  • S Karthikeyan
    Resveratrol modulates expression of ABC transporters in non-small lung cancer cells: Molecular docking and gene expression studies
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  • Robert D. Blackledge
    Anticipating an Advance in Forensic DNA
    | PDF Version
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    DNA IDENTIFICATION OF ANCIENT SKELETAL REMAINS IN SLOVENIA
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    | PDF Version
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    Molecular studies of Cumin (Cuminumcyminum L.), for diversity and modeling
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  • Kailash N Gupta
    Molecular characterization and phylogenetic analysis of Citrus mosaic Badna virus (CMBV) associated with Sathgudi sweet orange
    | PDF Version
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    Impact of rHu-Epo supplementation on CRF induced Neurobehavioral changes in rats: Studies on correlation with APP ratio, 脙聨脗虏 amyloid and pTau expression
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    Studies on the Combined Effect of Multi 脙垄芒聜卢芒聙聹 Walled Carbon Nano Tubes (MWCNTs) and Maleic Anhydride grafted Polypropylene (MA 脙垄芒聜卢芒聙聹 g PP) on the Mechanical and Thermal Properties of Polypropylene (PP)
    | PDF Version
  • I. G. Nweke
    Prevalence of Human Papilloma Virus DNA in HIV Positive Women in Lagos University Teaching Hospital (LUTH) Lagos, Nigeria
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    The use of constructed nano and micro-filtration membrane as a confine bioreactor for microbial growth and extracellular digestive enzymes secretion
    | PDF Version
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  • G C Gahlot
    Assessment of genetic variability in Marwari breed of Indian meat goat using Microsatellite DNA
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    Global Metabolic Changes and Cellular Dysfunction in Diamide Challenged G6PD-Deficient Red Blood Cells
    | PDF Version
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    Preclinical studies of glucocorticoid receptor antagonists in the treatment of alcohol dependence
    | PDF Version
  • A. E. Pillay
    Laser [213-nm] depth-profiling studies of v/ni ratios in asphaltenes following liquid nitrogen pre-treatment
    | PDF Version
  • Daniel Rotroff
    Using DNA copy number aberrations in naturally occurring canine cancers to identify candidate drivers of carcinogenesis
    | PDF Version
  • Nisreen E. Mahmoud
    Parasitological and comparative pathological studies on monogenean infestation of cultured sea bream (Sparus aurata, Sparidae) in Egypt.
    | PDF Version
  • Weijia Xie
    Recent structure relationship studies (SAR) on natural occurring sulfonium salts as potent 脙炉脗聛脗隆-glucosidase inhibitors
    | PDF Version
  • Klara Kubelkova
    The cellular basis of protective immunity against experimental infection caused by Francisella tularensis
    | PDF Version
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    Crosstalk between acidic phospholipids present in bacterial membranes and DnaA, the initiator of Escherichia coli chromosomal replication
    | PDF Version
  • Jeffrey Zheng
    Pseudo DNA Sequence Generation of Non-coding Distributions using Stream Cipher Mechanism
    | PDF Version
  • George W. Adams
    Novel Concepts for the Application of Rapid DNA Technology as a Sentinel Event Prophylactic in the Criminal Justice System
    | PDF Version
  • Irina Perepechina
    Development of the standard of the determination of genetic identity on the basis of the predetermined level of reliability of DNA identification
    | PDF Version
  • M. A. Salih
    Evaluation of Ethni-Test in the assessment of individual ethnic origin for forensic and medical applications
    | PDF Version
  • Meg Mangin
    Clinical Evidence of Immune System Dysregulation Caused by Intracellular Infection
    | PDF Version
  • Eman H.Abdel-Rahman
    Induction of protective cellular and humoral responses against fasciolosis in rabbits using immunoaffinity fraction of Fasciola gigantica excretory secretory products
    | PDF Version
  • Jeffrey S Patrick
    High Performance Gas Chromatography Mass Spectrometry in Addressing the Challenges of Metabolomic Studies 脙垄芒聜卢芒聙聹 Separation in Time and Mass
    | PDF Version
  • Enrique C. Samano
    An application of electron beam lithography: Location of metallic nanostructures based on DNA
    | PDF Version
  • Huseyin Cimen
    Discovery-based Targeted Proteomic Studies: Gel-based and/or off-gel protein sample preparation and purification
    | PDF Version
  • Chin Chiew Foan
    Probing molecular and cellular mechanisms in tissue culture samples of commercial crops using Proteomic approach
    | PDF Version
  • Trevor R.F. Smith
    Generation of robust immunity following DNA vaccine immunization enhanced by intradermal electroporation
    | PDF Version
  • Charles F. L. Mbakaya
    Elucidating the link between environment, nutrition, host immunity, AIDS and cancer as informed by selected studies in Kenya and beyond
    | PDF Version
  • Alexander V. Sirotkin
    New hormonal and intracellular regulators of reproduction
    | PDF Version
  • Maria ISAGULIANTS
    DNA vaccination against drug resistance in chronic viral infections, example of HIV-1
    | PDF Version
  • Subir Samanta
    Design, synthesis and antidiabetic, cardiomyopathy studies of cinnamic acid-amino acid hybrid analogs
    | PDF Version
  • Alexander D. Verin
    Extracellular purines in vascular endothelial barrier preservation
    | PDF Version
  • Robert M. Mentzer, Jr.
    The homeostatic intracellular repair response (HIR2) and autophagy during cardiac surgery
    | PDF Version
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