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ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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Human Papilloma Virus

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Human Papilloma Virus

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Human Papilloma Virus

Human Papilloma Virus is the most common sexually transmitted infection. Some types of these viruses can cause genital warts and cancers. Genital warts usually appear as a small bump or group of bumps in the genital area.However, if the infection is High risk, then there will be more chances of occurence of cervical cancer. Vaccination is recommended for the patients with compromised immune system. There will be no symptoms for HPV infection and the body clears the infection after few years. Recent research has shown that more than 90% of patients have no symtoms of the infection until two years.

Related Journals of Human Papilloma Virus

Journal of Infectious Diseases & Therapy, Bacteriology Journal,Clinical Infectious Disease Journal,Immunology Journal, Neuroinfectious Disease Journal, Pathology Journal,Virus Adaptation and Treatment, Virus Research, Viruses, Advances in Virus Research, Virology Journal, Virologica Sinica

Human Papilloma Virus

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    Classically, the 3脙垄芒聜卢芒聞垄untranslated region (3脙垄芒聜卢芒聞垄UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3脙垄芒聜卢芒聞垄UTR alone, without all other elements in mRNA such as 5脙垄芒聜卢芒聞垄UTR and coding region. The importance of independent 3脙垄芒聜卢芒聞垄UTR RNA (referred as I3脙垄芒聜卢芒聞垄UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3脙垄芒聜卢芒聞垄UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3脙垄芒聜卢芒聞垄UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3脙垄芒聜卢芒聞垄UTR were important for its tumor suppression activity. Then, the C/EBP 3脙垄芒聜卢芒聞垄UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3脙垄芒聜卢芒聞垄UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3脙垄芒聜卢芒聞垄UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990脙垄芒聜卢芒聞垄s to 2000脙垄芒聜卢芒聞垄s, world scientists found several 3脙垄芒聜卢芒聞垄UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3脙垄芒聜卢芒聞垄UTR regions, although the existence of their transcribed products as independent 3脙垄芒聜卢芒聞垄UTR RNAs is still to be confirmed. Our studies indicate that the independent 3脙垄芒聜卢芒聞垄UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
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    Plant virus expression vectors for biopharmaceutical production
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    Immune Responses to Human Papillomavirus Vaccines: What We Have Learned
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    Prevalence of Human Papilloma Virus DNA in HIV Positive Women in Lagos University Teaching Hospital (LUTH) Lagos, Nigeria
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    Autoimmune inflammation and the human microbiome
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    Haemogram and serum enzymes activities of Newcastle Disease Virus challenged broiler chickens following supplemental treatment with Aloe vera extract.
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    EFFECT OF NANOPARTICLES ON HUMAN CELLS FROM HEALTHY INDIVIDUALS AND PATIENTS WITH RESPIRATORY DISEASES
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    The new genetics of adeno-associated virus
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    Important Multiple Plant Viruses Present on Vegetable Crops in Kuwait
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    Harnessing human N-type Ca2+ channel receptor by identifying the atomic hotspot regions for its blocker design
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    Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden in pregnant mice
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