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Molecular cell is the study of how molecules interact to give rise to the properties of cells, their ability to grow, maintain themselves and divide. Molecular Cell examines how the interaction of macromolecules gives rise to life, i.e., to the functioning of living organisms. The integration of molecular structure, function, and behaviour can lead to a functional living cell. The structural dynamics of domains within macromolecules and subunits of macromolecular assemblies, through the integration of pathways and organelles, to the interactions of a cell with its immediate environment are elucidated. The integration generates new functional properties through the nonlinear, dynamic and spatial nature of the interactions between biological macromolecules. The perturbations of molecular structures and their interactions cause malfunction and disease.
Gong Deuk Bae Effect of liquiritigenin on apoptotic beta-cell death by palmitate-induced lipotoxicity in INS-1 cells
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Dong-Kyu Kim Cross-Talk between Human Mast Cells and Epithelial Cells by IgE-mediated Periostin Production in Eosinophilic Nasal Polyps
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Thomas Böldicke Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells
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Noelle Mathieu Bowel Radiation Injury : Complexity of the Pathophysiology and promise of Cell and Tissue Engineering
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Liwei Lu Leptin promotes B cell response in autoimmune arthritis
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Gerald J Prud`homme Gamma-aminobutyric acid (GABA) treatment blocks inflammatory pathways and promotes survival and proliferation of pancreatic beta cells
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Eva M Carmona The inflammasome of activated human B-cellsregulates IL-1β and IgM: A crosstalk between the innate and the adaptive immune response
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Jalil Mehrzd Bioluminescence-based detection of brain immune cells apoptosis and ATP depletion induced by aflatoxin B1
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Eva E Avila Interaction of the parasite Trichomonas vaginalis with human neutrophil extracellular traps
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Jessy S Deshane Longitudinal changes in airway microbiome signatures and immunoregulatory cell dynamics following Bronchial Thermoplasty
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Bozena Futoma-Koloch C3 component deposition on Salmonella O48 cells characterized by sialylated lipopolysaccharide and different pattern of outer membrane proteins
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Amina Dahmani TRANSFORMING GROWTH FACTOR-β PROGRAMS CENTRAL-MEMORY DIFFERENTIATION IN EX-VIVO STIMULATED HUMAN T CELLS BY MODULATING ID3 EXPRESSION
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Rongtuan Lin Modulating the Antioxidant Defences to Potentiate Oncolytic Virotherapy in Refractory Cancer Cells
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Moshe Giladi Tumor Treating Fields (TTFields) induced cancer cell death may be immunogenic resulting in enhanced antitumor efficacy when combined with immune-modulating therapy
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Masayuki Fukata Innate immune regulation of T-helper (Th) cell homeostasis in the intestine
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Daniel S Peiffer Dietary consumption of black raspberries or their anthocyanin constituents alters innate immune cell trafficking in esophageal cancer
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Elena Bonanno Microcalcification as an active phenomenon mediated by epithelial cells with mesenchymal characteristics
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Praveena T The structural and molecular insights into natural killer T cell receptor (NKT) and CD1d-glycolipid recognition
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Saroj Velamakanni Multiparameter analysis using cell cycle biomarkers for breast cancer: Prognostic and predictive implications
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Jan Voskuil How antibodies can prevent medical progress and how they can be great tools?
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T. B. Karegoudar Purification and Characterization of Amidase from Paracoccus sp. SKG: Utilization of amidase inhibited whole cells for bioconversion of acrylonitrile to acrylamide
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Monray Edward Williams Molecular validation of putative antimicrobial peptides for improved Human Immunodeficiency Virus diagnostics via HIV protein p24
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Gamal Wareth Investigation and molecular typing of Brucella isolated from dairy cattle herd immunized with Brucella abortus RB51 vaccine in Egypt
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Dana L Jacoby Optimizing urology group partnerships: Collaboration, compensation, and centers of excellence
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Yen-Chein Lai Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation
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Fathia El Sharkawi The effect of PTEN and TRAIL genes loaded on nanoparticles on hepatocellular carcinoma
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Geeta Shroff Improved Epilepsy and Speech Outcomes with Human Embryonic Stem Cell Therapy in Children with Cerebral Palsy
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Ilana Kolodkin-Gal Maintaining motile cells inside the biofilm through cell-to-cell signaling, transcription regulation and evolution
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Yosef Yarden Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
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Fan-Gang Tseng Fan-Gang-Tseng-National-Tsing-Hua-University-Taiwan-Nano-Micro-fluidic-systems-for-circulating-Tumor-Cells-(CTCs)-rapid-detection-and-diagnosis
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Guijun Wang Design, Synthesis and Characterization of Glycolipids and Glycoclusters as Molecular Gelators
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Agata Steenackers Physio-pathological properties of colon cells are regulated by the nucleocytoplasmic OGT
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Pi-Wan Cheng Disregulation of Golgi localization of glycosyltransferases alters mucin O-glycosylation and survival or metastatic properties of cancer cells
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Joseph R Purita The use of supplements and cytokines in platelet rich plasma injections and stem cell treatments
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Adel Nefzi “Adel Nefzi-Torrey-Pines-Institute-for-Molecular-Studies-USA-Diversity-Oriented-Synthesis-of-low-Molecular-Weight-Acyclic-and-Heterocyclic-Compounds-from-Resin-bound-Polyamides-Application-for-Drug-Discoveryâ€ÂÂ
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Christain Dani Human Induced Pluripotent Stem cells: A new source for brown and white adipocytes
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Justyna Trynda The role of microRNA-125b in calcitriol-induced differentiation of human leukemia and lymphoma cells
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Ewa Maj Antiangiogenic treatment in non-small cell lung cancer (NSCLC)
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Carmen Alvarez-Dominguez A dendritic cell targeted vaccine loaded with a GAPDH peptide confers wide protection to listeriosis in susceptible and resistant mice
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Nahla A El-Wakil Comparative study of enzymatic and chemical denaturation of wheat gluten and their cellulosic nanocomposites
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Alejandro RodrÃÂguez Integral utilization of lignocellulosic materials; residues of the agriculture and agri-food industry
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Arvind Jayant Evaluation of EOL/used cell phones management & disposal alternatives: An ANP and balanced scorecard approach
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Punit Kaur A Mouse Model for Triple-Negative Breast Cancer Stem Cells (TNBC-CSC) Exhibits an Aggressive Phenotype
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K Ludwig Targeting microtentacles on circulating breast tumor cells to reduce metastasis
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Arghya Adhikary PEGylated-thymoquinone-nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a
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Paul A Beavis Adenosine receptor 2A blockade increases the efficacy of anti-PD-1 through enhanced anti-tumor T cell responses
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Phillip K. Darcy Cancer immunotherapy utilizing gene-modified T cells: from the bench to the clinic.
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Rivan Sidaly Hypoxia increases the expression of enamel proteins and cytokines in an ameloblast-derived cell line
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Vikram Kalpande Kharif sorghum genotype SPV 1786 with excellent quality characters and high yield
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S Karthikeyan Resveratrol modulates expression of ABC transporters in non-small lung cancer cells: Molecular docking and gene expression studies
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Jan O Gordeladze Key regulatory junctions stabilizing the osteoblast phenotype: Implications for cell and tissue engineering
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Yamina Andre Nanostructured self-assembled P3HT thin films and their application to enhance organic solar cell efficiency
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Xuejun H Parsons Direct conversion of pluripotent human embryonic stem cells into functional human neuronal or cardiomyocyte cell therapy derivatives for regenerative medicine
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John S Pixley Generation of long-term human pancreatic islet cell activity in vivo by induction of immune tolerance to human stem cells
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Dinesh Keerty Efficacy and safety of low molecular weight heparin compared to unfractionated heparin for chronic outpatient hemodialysis in end stage renal disease: Systematic review and meta-analysis
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Dragos C Luca Anaplastic large cell lymphoma, ALK-positive, small cell variant, with leukemic presentation and rare CD8-positive phenotype
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Antonio Cilla Antiproliferative effect of main dietary phytosterols and/or β-cryptoxanthin in human colon cancer Caco-2 cells through cytosolic Ca2+ - and oxidative stress-induced apoptosis
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Myron R Szewczuk Novel signaling paradigm regulating TOLL-like receptors on innate immune cells
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Gao Peisong Functional Effects of TGF-beta1 on Mesenchymal Stem Cell Mobilization in Cockroach Allergen Induced Asthma
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Nancy J Bigley Differential expression of SOCS1/SOCS3 ratios in virus-infected macrophage cell lines
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Dele Ogunremi Strategy for developing a molecular sub typing tool for a food borne bacterial pathogen using a whole genome analysis approach: the case of Salmonella Enteritidis
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Aravind Jukanti Diversity analysis (genetic, molecular and gum content) of Cluster Bean (Cyamopsis tetragonoloba L.) - An emerging industrial crop
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Dequan Xiao Inverse molecular design of green catalysts for biomass conversion
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Gita Kumari Application of MLVA-15 genotyping for typing of Brucella abortus isolates from India
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David Y Lai Mechanism-based molecular design of chemicals with low carcinogenicity potential
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Jack Sung Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia (AGA) by Activating Hair Follicle Stem Cells
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Madhu Choudhary Lignocellulolytic activity of soil fungi isolated from different scenarios of Conservation Agriculture
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Rajasri Mandali Molecular characterization and management of Tomato leaf curl virus and its vector, B. tabaci, using cultural methods like guard crops and mulches in Tomato
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Kailash N Gupta Molecular characterization and phylogenetic analysis of Citrus mosaic Badna virus (CMBV) associated with Sathgudi sweet orange
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Chien-Fu Hung Mark cancer cells for CTL attack through coating with viral antigenic peptides CTLs kill tumor with viral peptides
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Ofir Menashe The use of constructed nano and micro-filtration membrane as a confine bioreactor for microbial growth and extracellular digestive enzymes secretion
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Rajesh Kumar Vaid Isolation and molecular identification of Moraxella ovis and Moraxella spp. from Infectious Keratoconjunctivitis in sheep in India
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Rajib Deb Molecular characterization and identification of SNP at promoter region of bovine ITGB6 receptor gene
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Ping Xie Molecular mechanisms of B lymphomagenesis induced by TRAF3 inactivation
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Kazuya Kubo Structure and Physical Properties of Ferromagnetic Crystals with Supramolecular Cations
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Lois J Arend Novel roles for PKD genes in the reproductive tract and in stromal cells of the kidney
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William Lee Regulatory roadmap for initiating a cell therapy drug into clinical trials in the US
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Daniel Tsun-Yee Chiu Global Metabolic Changes and Cellular Dysfunction in Diamide Challenged G6PD-Deficient Red Blood Cells
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Reem J Farid Alteration of B & T cell markers in chronic granulomatous disease patients
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Smith I Jaja L-Arginine supplementation enhances antioxidant activity and erythrocyte integrity in sickle cell anemia subjects
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Dike O. Ukuku Bacterial cell surface charge, attachment and decontamination on melon rind surfaces
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Kay L. Medina Deciphering HoxA9 function in multipotential progenitor biology and B cell development
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Rafael Correa-Rocha HIV infection of Human regulatory T cells (Treg) downregulates Foxp3 expression and produces a loss of the suppressive capacity of these cells
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Lourdes Cortes-Dericks ALDHhigh/CD44+ putative cancer stem cell population as therapeutic target in malignant pleural mesothelioma
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Qiao Li Potential of small molecule inducers in cell-based therapeutics
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Maria Vittoria Barone Lactobacillus paracasei CBA L74 prevents entrance of undigested gliadin peptides and rotavirus in Caco-2 cells
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R K Tanwar Brucellosis in cattle & buffaloes in and around Bikaner, Rajasthan, India
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Marlous Dillingh Characterization of inflammation and immune cell modulation induced by lowdose LPS dose administration to healthy volunteers
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Ivan Mfouo-Tynga Effects of SulfonatedZinc Phthalocyanine and Low Intensity Laser Irradiation in Inducing Photodynamic Damagein Breast Cancer Cells
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Iqbal Parwez Genetic diversity and molecular declining population of four Channid species from North India and possible strategies
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Yuka Kobayashi Molecular design and electronic properties of new doping system: pure organic TTF-based salt-bridged crystals
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Stefanie Wienkoop Comprehensive Protein turnover analysis of a partial 15N stable isotope metabolic labelling experiment In Planta
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Klara Kubelkova The cellular basis of protective immunity against experimental infection caused by Francisella tularensis
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Ji-Zhong Bai Astrocytic contribution to deficient Ca2+ signalling and oxidative stress mediated by TRPV4 channels in A40-induced hippocampal cell death
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Meg Mangin Clinical Evidence of Immune System Dysregulation Caused by Intracellular Infection
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Eman H.Abdel-Rahman Induction of protective cellular and humoral responses against fasciolosis in rabbits using immunoaffinity fraction of Fasciola gigantica excretory secretory products
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Vincenza Dolo Critique in vitro analysis of platelet concentration effect on cells involved in in-vivo wound healing
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Paul H. Lerou Exploring human pluritotent stem cell heterogeneity using a multi-scale imaging and informatics pipeline
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Nguyen Linh Toan Molecular impacts of virus infections and genetic variants on the course of HBV-related liver diseases in Vietnam
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Kelvin K. Tsai Linking tissue microarchitectures to rationalized molecular diagnostics in glandular cancers
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Diana Anderson EFFECT OF NANOPARTICLES ON HUMAN CELLS FROM HEALTHY INDIVIDUALS AND PATIENTS WITH RESPIRATORY DISEASES
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Reinaldo Barros Geraldo Looking for β3 integrin family selectivity: The use of snake venom disintegrin as a tool for molecular modeling approach
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Paul J. Davis Nanotetrac targets the thyroid hormone receptor on integrin αvβ3 on tumor cells to promote apoptosis, disorder cell defense pathways and block angiogenesis
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Vasiliki E. Kalodimou The effects of infused mesenchymal stem cells obtained by adipose tissue (ADSCs) to treat chronic scar tissue of the vocal cords in an animal model
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Stefano Varrella Molecular response to toxic diatom-derived aldehydes in the sea urchin Paracentrotus lividus
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Amparo Pascual-Ahuir Giner Real time analysis of gene expression in living yeast cells: Novel approach for accurate cell damage detection
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Miguel Rechichi Intraoperative in-vivo oct pachymetric mapping during epi-off pulsed accellerated high fluence corneal collagen cross-linking with dextran free riboflavin
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Maria Teresa Mascellino Candida bloodstream infections: species distribution and antifungal resistance in General Medicine wards and in Intensive Care Units (ICUs)
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