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Determination of Tacrolimus in Rat Whole Blood Utilizing Triple Quadrupole LC/MS
A simple, sensitive and rapid method was developed for quantitation of tacrolimus in rat whole blood utilizing triple Quadrupole LC/MS. An aliquot of 0.1 mL of whole blood sample was extracted with t-butyl methyl ether using a Heidolph vortexer. The chromatographic separation was performed by using chromolith fast gradient HPLC RP 18e (2mmX50mm... Read More»
A. R. Suresh Babu, B. Thippeswamy and A. B. Vinod
Research Article: J Anal Bioanal Techniques 2011, 2:118
DOI:
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