Journal of Oncology Research and Treatment
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Arwa Tagoug
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Novel RNA Polymerase I Inhibitor CX-5461 Exhibits Antitumor Activity in Multiple Myeloma
rDNA transcription is steadily dysregulated in multiple myeloma, through oncogenes and anti-tumor routes, and particularly by c-Myc. The main downstream goals of c-Myc involve ribosomal biogenesis to enhance the protein translation capacity necessary to support the growth and self-renewal programs of malignancy cells. In the research of therapeutic... Read More»
: J Oncol Res Treat
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