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Objectives: Protein binding decreases antibacterial activities as the free fraction only crosses membranes thus reaching intracellular targets. However, serum components may also increase antibacterial activities. Therefore, the effect of serum proteins on activities of ß-lactams, macrolides, and fluoroquinolones was examined. Several preparat... Read More»
Axel Dalhoff and Sabine Schubert
Research Article: J Clin Infect Dis Pract 2016, 1:110
DOI:
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