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Mrinmoy Saha Ph.D
Senior Scientist
ABZENA
USA
E-mail: sahamrinmoy13@gmail.com
EDUCATION:
Oregon State University, Corvallis, Oregon - 2008-2014 Ph. D. Synthetic Organic Chemistry
Indian Institute of Technology Guwahati, India - 2005-2007 M. Sc. Chemistry
University of Calcutta, Kolkata, India - 2002-2005 B. Sc. Chemistry
JOB EXPERIENCE:
Senior Scientist - 02/2017- Present
Abzena, Bristol, Pennsylvania
As a senior scientist, playing major role in preparation, purification and characterization (using analytical techniques) of
biologically important molecules in a safe environment. Working on Abzena’s R&D projects related to synthesis of ADC (Antibody-Drug Conjugates).
Responsible for day-to-day management of chemical laboratories and lab personnel.
Post Doctoral Fellow with Dr. Daniel Appella 02/2015-01/2017 NIDDK, National Institutes of Health, Bethesda, Maryland.
Developed a series of small molecule drugs to inhibit Wip1 phosphatase. Executed design and synthesis of HIV-1 nucleocapsid protein inhibitors. Worked on synthesis of both solid and solution phase peptides and peptide nucleic acids (PNAs) and associated monomers for detection of nucleic acids as well as for multivalent display.
Doctoral Studies (Ph.D.) with Professor Rich Carter 12/2008-11/2014 Oregon State University, Corvallis, Oregon.
Dissertation “A Unified Approach for The Total Synthesis of C10-Functionalized Lycopodium Alkaloids”. Completed total syntheses 10-hydroxylycopodine, deacetylpaniculine, and paniculine. Optimized an organocatalyzed diastereselective heteroatom Micheal reaction toward the eastern fragment of himeradine A. Synthesized the common intermediate towards the total synthesis of himeradine A and other related natural products such as lycopecurine, fastigiatine and inundatine. Worked on the Synthesis the C5 epimer of the natural product cermizine C in our group’s synthetic efforts towards cermizine C and cermizine D. Carried forward starting material in our group’s synthetic studies toward azaspiracid-1. Harvested the club moss Lycopodium Clavatum and isolated different natural products.
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