黑料网

Animal biotechnology; Agriculture; Organism's genome; Environmental footprint

Introduction

Animal biotechnology, a field at the intersection of genetics, biology, and technology, has seen remarkable advancements in recent years. This discipline focuses on the application of molecular and cellular techniques to improve the health, welfare, and productivity of animals, with far-reaching implications for agriculture, medicine, and conservation. In this article, we will explore the key aspects and potential benefits of animal biotechnology [1]. Genetically modified animals can be designed to yield higher-quality products, improve disease resistance, and reduce the environmental footprint of livestock farming. This has the potential to address food security challenges and reduce the use of antibiotics and growth-promoting hormones. However, it also raises concerns about the long-term effects on ecosystems, animal welfare, and human health. Conservation efforts benefit from biotechnology by facilitating the preservation of endangered species through techniques like cloning and assisted reproductive technologies [2]. These tools can help prevent species extinction and restore biodiversity, but ethical dilemmas surrounding the authenticity of resurrected populations and the allocation of resources persist.

Genetic modification for agriculture

One of the most prominent applications of animal biotechnology is genetic modification for agriculture. Through selective breeding and genetic engineering, scientists have developed livestock breeds that exhibit desirable traits such as disease resistance, enhanced growth, and improved feed conversion efficiency. This has led to increased agricultural productivity and more sustainable farming practices [3]. For example, genetically modified salmon can reach market size faster, reducing the environmental impact of aquaculture.

Disease resistance

Animal biotechnology has also been instrumental in developing animals with increased resistance to diseases. For instance, researchers have created genetically modified pigs that are resistant to specific diseases like African swine fever, a devastating virus affecting the global swine industry. Such advancements have the potential to reduce the need for antibiotics and improve animal welfare [4].

Biopharmaceutical production

Animals are increasingly being used as bioreactors to produce valuable proteins and pharmaceuticals. This approach, known as biopharming, involves genetically modifying animals, such as goats or rabbits, to express human proteins in their milk or eggs. These proteins can then be harvested and used in the production of therapeutic drugs, vaccines, and other medical products [5].

Conservation efforts

Animal biotechnology plays a vital role in conservation efforts by aiding in the preservation of endangered species. In vitro fertilization, cloning, and assisted reproductive techniques have been used to help revive dwindling populations and safeguard genetic diversity [6]. For example, the successful cloning of endangered species like the northern white rhinoceros offers hope for their long-term survival.

Human health

Animal biotechnology has significant implications for human health. Pigs, for instance, are being genetically engineered to produce organs suitable for transplantation into humans [7]. This could address the shortage of organ donors and save countless lives. Additionally, animals are used in research to better understand human diseases and develop new therapies [8, 9].

Challenges and ethical considerations

While animal biotechnology holds immense promise, it also raises ethical concerns and challenges. These include questions about animal welfare, ecological impacts, and the potential for unintended consequences. Striking a balance between technological advancement and ethical considerations is crucial in this field [10].

Conclusion

Animal biotechnology is a dynamic and evolving field with farreaching implications for agriculture, medicine, and conservation. As scientists continue to make breakthroughs in genetic modification, disease resistance, and biopharmaceutical production, it is essential to remain vigilant in addressing ethical concerns and ensuring that these advancements benefit both humans and animals. The responsible and ethical use of animal biotechnology holds the key to a sustainable and brighter future for both the animal kingdom and humanity as a whole.

1. Said S, Putra WPB, Anwar S, Agung PP, Yuhani H (2017) Phenotypic, morphometric characterizations and population structure of Pasundan cattle at West Java, Indonesia.  Biodiversitas 18:1638-45.

Indexed at, Google Scholar, Crossref

2. Sutikno S, Priyanto R, Sumantri C, Jakaria J (2018) Polymorphism of ADIPOQ and EDG1 genes in Indonesian beef cattle. J Indon Trop Anim Agric 43: 323-32.

Google Scholar, Crossref

3. Putra WPB, Anwar S, Said S, Indratno RAA, Wulandari P (2019) Genetic characterization of Thyroglobulin and Leptin genes in Pasundan cattle at West Java. Bullet Anim Sci 43: 1-7.

Indexed at, Google Scholar, Crossref

4. Volkandari SD, Nadila A, Radiastuti N, Margawati ET (2018) Genetic polymorphismof Calpastatin (CAST) gene in Pasundan cattle. Bullet Anim Sci 42: 262-66.

Indexed at, Google Scholar

5.  Sutikno S, Priyanto R, Sumantri C, Jakaria J( 2019) Identifikasi keragaman gen FTO pada bangsa sapi potong Indonesia. JITRO 6:240-46.

Indexed at, Crossref

6. Putra WPB, Agung PP, Said S (2019) The polymorphism in g.1256G>A of bovine pituitary specific transcription factor-1 (bPIT-1) gene and its association with body weight of Pasundan cattle. J Indon Trop Anim Agric 44: 19-27.

Indexed at, Google Scholar, Crossref

7. Putra WPB, Agung PP, Anwar S, Said S (2019) Polymorphism of bovine growth hormone receptor gene (g.3338A>G) and its association with body measurements and body weight in Pasundan cows. Trop Anim Sci J 42: 90-96.

Indexed at, Google Scholar, Crossref

8. Agung PP, Said S (2014) Introduction Belgian Blue cattle in Indonesia: An evaluation on sperm and confirmation of myostatin gene mutation. Proc Anim Sci 1523-26.

Google Scholar

9. Agung PP Said S, Sudiro A (2016) Myostatin gene analysis in the first generation of the Belgian Blue cattle in Indonesia. J Indon Trop Anim Agric 41: 13-2.

Indexed at, Google Scholar, Crossref

10. Putra WPB, Agung PP, Said S (2018) Non-genetic factor and genetic parameter analysis for growth traits in Sumba Ongole (SO) cattle .J Indon Trop Anim Agric 43: 94-06.

Indexed at, Google Scholar, Crossref