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Current problems and costs, economically, medical, legal and personal, local pain medications and chronic pain treatment are never ending. Substance use disorder is drug use despite the side effects. This condition includes drug resistance, high craving for drugs and difficulty in reducing drug use. Withdrawal symptoms may include insomnia, nausea, muscle aches, and diarrhea. Diacetylmorphine is used as a mindaltering drug. It also includes side effects such as shortness of breath, drowsiness, and addiction. Its therapeutic objectives include pain medications such as trauma, postoperative pain or heart disease. Physical symptoms include stretching, yawning, sneezing, tremors, high pain, high blood pressure, fever, light sensitivity, restlessness and vomiting. Drug overdoses, both lethal and non-lethal are common. Most homicides happen at home, with a few seemingly intentional. Recent studies show that disturbed breathing during non-REM sleep increases with opioid dosage. The powerful effect of the drug on respiratory distress between both animals and humans is well documented. Substance use disorder impairs perception and emotional distress, and contributes to poor judgment. Forced use due to addiction leads to loss of control and dangerous use of the drug and side effects. Buprenorphine used to treat pain and addiction. Side effects of buprenorphine include neural inhibition, postural hypotension, weight loss, dry mouth, and effects on the central nervous system, memory loss and dizziness. Benzodiazepines are commonly prescribed to treat opioid-related anxiety and depression. When a medical professional writes these instructions, patients and physicians alike often fail to make significant interactions and interactions between these drugs and the opposite effects available. Although there is evidence that severe pain from opioid medications in the short term, there is no significant evidence of improved physical activity or maintenance of pain relief for long-term remission. Methods of loss of analgesic efficacy include the development of pharmacologic tolerance and opioid-induced hyperalgesia, addiction and dependence. Pain management with opioid medications is a commonly discussed and related topic. Opioid drugs have been prescribed since ancient times although they are known to cause severe and consistent adverse reactions. Depression and anxiety are the most common co-morbid-related moods seen in patients receiving opioid treatment. In many cases, the pain medication provider and the psychiatric provider are different, making it difficult to diagnose and treat. Symptoms of depression and anxiety are usually not given in opioid medications. Opioids cause concern over increased dependence and withdrawal as evidenced by the need for a daily dose of opioids. To treat substance use disorders caused by anxiety and depression associated with chronic opioid use, physicians often prescribe anxiolytics such as benzodiazepines. Benzodiazepines significantly increase both drug-induced stress and anxiety. Additionally, three or more of the following methods should be developed during withdrawal: dysphoric condition, nausea or vomiting, muscle aches, lacrimation or rhinorrhea, pupillary dilation, piloerection or sweating, diarrhea, yawning, fever. These symptoms should cause significant clinical stress in the community, workplace or other important workplace and may be caused by other mental disorders or withdrawal or intoxication. It is often recognized that the use of recreational drugs is often harmful to one's mental and physical health. It is a problem that such effects are rarely considered when psychiatric medications are prescribed. The psychological effects of psychotropic drugs, such as opioids, prevent users from experiencing the underlying personal and psychological problems, environmental pressures, building good social relationships all of which improve the chances of long-term recovery.

The authors are grateful to the journal editor and the anonymous reviewers for their helpful comments and suggestions.

The authors declared no potential conflicts of interest for the research.