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ISSN: 2168-9652

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  • Case Report   
  • Biochem Physiol,
  • DOI: 10.4172/2168-9652.1000320

3-Nitrotyrosine Used as Biomarker for The Vasculopathy

Jiangnan Zhao
*Corresponding Author :

Jiangnan Zhao



Abstract

The endothelial dysfunction of Fabry disease results from αgalactosidase A deficiency resulting in the buildup of globotriaosylceramide. Vasculopathy within the α-galactosidase A null mouse is manifested as oxidant-induced thrombosis, accelerated atherogenesis, and impaired arterial reactivity. to raised understand the pathogenesis of Fabry disease in humans, we generated a person's cell model by using RNA interference

Keywords: 3-Nitrotyrosine

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