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Abstract

Obsessive-Compulsive and Related Disorders (OCRDs) encompass a group of conditions characterized by repetitive, intrusive thoughts (obsessions) and/or ritualistic behaviors (compulsions). These disorders significantly impact daily functioning and quality of life. The spectrum includes Obsessive-Compulsive Disorder (OCD), Body Dysmorphic Disorder (BDD), Hoarding Disorder (HD), TrichoTilloMania (TTM), and excoriation (skin-picking) disorder. This review explores the clinical features, underlying neurobiological mechanisms, and treatment approaches for OCRDs. Cognitive-Behavioral Therapy (CBT), particularly Exposure and Response Prevention (ERP), remains the gold standard for treatment, often supplemented by pharmacotherapy with Selective Serotonin Reuptake Inhibitors (SSRIs). Emerging research into the genetic and neurobiological underpinnings of OCRDs is shedding light on novel therapeutic targets, offering hope for more effective and personalized interventions. Understanding the complex interplay of genetic, environmental, and psychological factors in OCRDs is crucial for advancing diagnostic precision and treatment efficacy

Keywords: Body dysmorphic disorder, Trichotillomania.