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Abstract

Bio-materials composed of calcium phosphate (CaP) have gained significant attention for their potential in regenerating cranio-maxillofacial bone defects. This abstract explores the physicochemical properties and biomedical applications of CaP biomaterials, focusing on their ability to mimic the natural composition of bone tissue and promote osteogenesis. Key properties such as biocompatibility, bioactivity, and osteoconductivity are discussed, highlighting their role in facilitating bone regeneration processes. The review also examines various forms of CaP biomaterials, including hydroxyapatite (HA) and tricalcium phosphate (TCP), and their respective advantages in promoting bone healing. Future directions in research and clinical applications of CaP biomaterials for cranio-maxillofacial surgeries are considered, emphasizing their potential to address critical challenges in reconstructive surgery and improve patient outcomes.