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Abstract

Bench-top mass spectrometry (MS) has emerged as a powerful tool in clinical diagnostics, offering unparalleled sensitivity, specificity, and speed for the analysis of organic compounds. This review explores the advancements and applications of bench-top MS in clinical organic chemistry. We discuss the principles of MS, instrumentation, and sample preparation techniques tailored for clinical specimens. Furthermore, we highlight the diverse applications of bench-top MS in clinical settings, including drug monitoring, disease biomarker discovery, and metabolic profiling. Additionally, we examine the challenges and future directions of bench-top MS in clinical organic chemistry, such as standardization, data analysis, and integration with other analytical techniques. Overall, bench-top MS holds immense promise for enhancing clinical diagnostics and improving patient outcomes in organic chemistry-related healthcare.