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Abstract

A crucial metabolic pathway in the mitochondria of eukaryotic cells is the Krebs cycle, also known as the citric acid cycle or the tricarboxylic acid cycle. The acetyl-CoA molecules produced by the breakdown of proteins, carbohydrates, and fats are further metabolized during this cycle to produce ATP, which is the energy source. In this article, we will zero in on the breakdown of proteins during the Krebs cycle. Amino acids make up the complex macromolecules known as proteins, which are necessary for the development and upkeep of the body's tissues. Proteins must be broken down into their individual amino acid components for the body to use them as a source of energy. Protein catabolism is the name given to this process. Enzymes in the stomach and small intestine break down dietary proteins into smaller peptide chains and individual amino acids, which is where protein catabolism begins. After that, these amino acids are brought to the liver, where they undergo additional processing and may enter the Krebs cycle [1, 2].