Research Article
Application of Monooxygenases in Dehalogenation, Desulphurization, Denitrification and Hydroxylation of Aromatic Compounds
| Pankaj Kumar Arora1, Alok Srivastava2* and Vijay Pal Singh2 | |
| 1Environmental Biotechnology, Microbial Type Culture Collection and Gene Bank (MTCC), Institute of Microbial Technology, Sector-39A, Chandigarh-160036, India | |
| 2Department of Plant Science, Faculty of Applied Sciences, M.J.P. Rohilkhand University, Bareilly -243006, India | |
| Corresponding Author : | Alok srivastava Department of Plant Science Faculty of Applied Sciences Rohilkhand University, Bareilly-243006, India Tel. +919760821347 E-mail: alok.plsc@rediffmail.com |
| Received October 25, 2010; Accepted November 25, 2010; Published November 27, 2010 | |
| Citation: Arora PK, Srivastava A, Singh VP (2010) Application of Monooxygenases in Dehalogenation, Desulphurization, Denitrification and Hydroxylation of Aromatic Compounds. J Bioremed Biodegrad 1:112. doi: 10.4172/2155-6199.1000112 | |
| Copyright: © 2010 Arora PK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. | |
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Abstract
Monooxygenases act as biocatalysts in bioremediation process and synthetic chemistry due to their highly regioselectivity and sterioselectivity on wide range of substrates. They are involved in the process of desulfurization, dehalogenation, denitrification, ammonification, hydroxylation, biotransformation and biodegradation of various aromatic and aliphatic compounds. In the recent years, the practical applications of monooxygenases have been improved using the approaches of directed evolution, meta-genomics and bioinformatics. This review is focused on current applications of monooxygenses especially in biodegradation and biotransformation of aromatic compounds.
