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Abstract

The public health sector has a global problem with antibiotic resistance, which is also a significant issue in Ethiopia.Due to the lack of a thorough examination, it is extremely challenging to report the trend of bacterial antibiotic resistance in Ethiopia. The objective of this systematic review was to present a summary of the literature on the pattern of antibiotic resistance of particular bacterial isolates that can be found in various clinical samples in Ethiopia. It encompasses the majority of Ethiopia's regions. The isolates' patterns of resistance ranged from 0% to 100%. M. tuberculosis has an overall resistance to ant tuberculosis medicines that ranges from 0% to 32.6%. When it comes to cases of tuberculosis that have already received treatment, the resistance rate rises. The majority of the antibiotics tested against Neisseria gonorrhoea, S. typhimurium, S. Virchow, Group A Streptococci (GAS), and Group B Streptococci (GBS) were highly effective against them. With a slightly higher susceptibility to gentamycin, Methicillin-Resistant Staphylococcus aureus was highly resistant to the majority of drugs. There were 28 total bacterial isolates discovered from various sample sources and geographical regions, including M. tuberculosis. Antibiotics that are often used were resistant to the majority of the bacterial isolates.