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Abstract

In the evolving landscape of cancer treatment, combination therapies have emerged as a pivotal approach to enhance therapeutic efficacy and overcome limitations associated with monotherapy. By integrating various treatment modalities—such as chemotherapy, immunotherapy, targeted therapy, and radiotherapy—combination therapies aim to address the complexity of cancer biology and improve patient outcomes. This article delves into the rationale behind combination therapies, their clinical applications, and the benefits they offer over traditional monotherapy. Through a comprehensive literature review, case studies, and expert interviews, we explore the mechanisms of action, challenges, and future directions of combination therapies in oncology. Ultimately, we conclude that combination therapies represent a transformative strategy in cancer treatment, offering new hope for improved survival rates and quality of life for patients.