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Abstract

Blood-based tumor detection has emerged as a promising tool in precision oncology, offering real-time, non- invasive methods to assess tumor presence, genetic mutations, and molecular dynamics. Techniques like liquid biopsy, which analyze circulating tumor DNA (ctDNA), RNA, and other biomarkers, can help guide surgical decisions by providing molecular insights into tumor localization, surgical margin assessment, and monitoring of minimal residual disease. This article explores the role of blood-based tumor detection in improving surgical outcomes, its clinical applications, challenges, and future directions for integration into routine cancer care