By Modulating Microglia via the TLR4/Myd88/NLRP3/Casp1 Pathway, Endometrial Stem Cells Isolated by Menstrual Blood Suppress Neuroinflammation
Received Date: May 03, 2023 / Published Date: May 29, 2023
Abstract
Many neurological illnesses frequently result in neuroinflammation as a reaction. A possible therapeutic for conditions linked to neuroinflammation is mesenchymal stem cell therapy. Mesenchymal stem cell effects are debatable, and the underlying process is not well known. In the current study, a mouse model of neuroinflammation created by peripheral lipopolysaccharide injection received an intravenous transplant of endometrial stem cells generated from menstrual blood. Endometrial stem cell-derived conditioned media was used to cultivate microglial cells that had been exposed to lipopolysaccharide.
Citation: Campbel B (2023) By Modulating Microglia via the TLR4/Myd88/NLRP3/Casp1 Pathway, Endometrial Stem Cells Isolated by Menstrual Blood SuppressNeuroinflammation. Arch Sci 7: 152.
Copyright: © 2023 Campbel B . This is an open-access article distributed underthe terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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