CRISPR-Cas9 in Bioterrorism: Potential Misuses and Mitigation Strategies
*Corresponding Author: Anshuman Singh, Defensive Biological Warfare, Biosecurity Fellowship, India, Email: anus_singh200@hotmail.comReceived Date: Jun 02, 2024 / Published Date: Jul 30, 2024
Citation: Anshuman S (2024) CRISPR-Cas9 in Bioterrorism: Potential Misuses and Mitigation Strategies. J Bioterr Biodef, 15: 402.
Copyright: © 2024 Anshuman S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The CRISPR-Cas9 genome editing technology has revolutionized the fields of genetics and biotechnology, offering unprecedented precision in modifying DNA sequences. While this tool holds immense promise for advancing medical research, agriculture, and biotechnology, it also raises significant concerns regarding bioterrorism. The ease and efficiency with which CRISPR-Cas9 can alter genetic material pose potential risks if misused for malicious purposes, including the creation of pathogenic organisms or the enhancement of biological agents for bioterrorism. This paper examines the dual-use nature of CRISPR-Cas9 technology, focusing on its potential applications in bioterrorism and the associated security implications. We explore the technological capabilities of CRISPR-Cas9, its potential misuse scenarios, and the ethical and regulatory challenges that arise. Through a review of current literature, case studies, and expert opinions, we assess the measures needed to mitigate the risks of CRISPR-Cas9 being used for bioterrorism. The paper aims to provide actionable recommendations for researchers, policymakers, and security professionals to enhance oversight and safeguard against the misuse of this powerful technology.