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Abstract

Cytokine Storm Syndrome (CSS) is a severe and potentially life-threatening condition characterized by an uncontrolled immune response and systemic inflammation. This abstract provides a comprehensive overview of CSS, focusing on its causes, consequences, and therapeutic strategies. Triggered by various stimuli such as infections, autoimmune reactions, or immunotherapy treatments, CSS leads to the rapid release of pro-inflammatory cytokines and can result in multiorgan dysfunction and mortality. Therapeutic approaches include anti-inflammatory agents, immunomodulatory therapies, supportive care, and targeted therapies aimed at attenuating the cytokine cascade and mitigating tissue damage. Understanding the pathophysiology of CSS and implementing timely interventions are crucial for improving patient outcomes and addressing the clinical challenges posed by this complex syndrome.