Deciphering the Dynamics: Exploring Etanercept Pharmacokinetics
Received Date: Feb 01, 2024 / Accepted Date: Feb 28, 2024 / Published Date: Feb 28, 2024
Abstract
Etanercept is administered via subcutaneous injection, with gradual absorption into the bloodstream and peak serum concentrations achieved within 72 hours. Its distribution is primarily limited to the intravascular compartment, with preferential localization in inflamed tissues. Unlike small molecule drugs, etanercept undergoes proteolytic degradation by endogenous enzymes, leading to predictable kinetics and minimal potential for drug-drug interactions related to metabolism. This abstract provides a concise overview of etanercept pharmacokinetics, unraveling its Absorption, Distribution, Metabolism, and Excretion (ADME) processes. Etanercept is administered via subcutaneous injection, with gradual absorption into the bloodstream and peak serum concentrations achieved within 72 hours. Its distribution is primarily limited to the intravascular compartment, with preferential localization in inflamed tissues. Unlike small molecule drugs, etanercept undergoes proteolytic degradation by endogenous enzymes, leading to predictable kinetics and minimal potential for drug-drug interactions related to metabolism.
Citation: Elizabeth D (2024) Deciphering the Dynamics: Exploring EtanerceptPharmacokinetics. J Pharmacokinet Exp Ther 8: 223.
Copyright: © 2024 Elizabeth D. This is an open-access article distributed underthe terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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