Research Article
Development and Validation of a Liquid Chromatographic/Mass Spectrometric Method for the Determination of Saikosaponin a in Rat Plasma and its Application to Pharmacokinetic Study
Shi-jia Liu1*, Zi-xiu Liu2, Wen-zheng Ju1, Ling Zhou2, Min Chen1, Jun zhang1 and Heng-shan Tan31Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing 210029, Jiangsu, China
2Nanjing University of Traditional Chinese Medicine, Nanjing 210029, Jiangsu, China
3General Hospital of Nanjing Military Base, Nanjing 210002, Jiangsu, China
- *Corresponding Author:
- Shi-jia Liu
Affiliated Hospital of Nanjing University of Traditional Chinese Medicine
Nanjing 210093, China
Tel: 86-25-86617141
Fax: 86-25-86555033
E-mail: snow8185@yahoo.com.cn
Received date: September 13, 2010; Accepted date: October 11, 2010; Published date: October 13, 2010
Citation: Liu SJ, Liu ZX, Ju WZ, Zhou L, Chen M, et al. (2010) Development and Validation of a Liquid Chromatographic/ Mass Spectrometric Method for the Determination of Saikosaponin a in Rat Plasma and its Application to Pharmacokinetic Study. J Anal Bioanal Tech 1:104. doi: 10.4172/2155-9872.1000104
Copyright: © 2010 Liu SJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
