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Abstract

Metabolomics, an emerging field within clinical pharmacology, provides a comprehensive analysis of endogenous and exogenous metabolites, offering insights into drug metabolism, efficacy, and toxicity. This abstract explores the pivotal role of metabolomics in unraveling drug metabolism. By employing high-throughput analytical techniques, metabolomics elucidates metabolic pathways, identifies biomarkers, and enhances our understanding of inter individual variability in drug response. Integration with pharmacogenomics enables personalized medicine approaches, while metabolic profiling facilitates drug safety assessment and disease monitoring. As metabolomics continues to advance, it holds promise for optimizing drug development and clinical decision-making, ultimately improving patient outcomes in diverse therapeutic areas.