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Abstract

Background: Hypertension is a common medical problem that complicates pregnancy. It may be, manifested as chronic hypertension, chronic hypertension with super imposed preeclampsia, Pregnancy induced hypertension, preeclampsia (PE) or eclampsia (E). This study will focus on the use of Magnesium sulphate (MgSO4) in PE/E. MgSO4 is the main drug of choice for the treatment/prevent PE and eclampsia.

Objective: The main objective of this study was to assess the utilization of Mgso4 in the obstetrics ward of Ras Desta Damtew Memorial Hospital.

Methods: Retrospective cross-sectional study design was employed by review of 87 patient charts. Purposive sampling technique was used to draw the charts.

Results: A total of 87 patient charts were reviewed. The majority of mothers were within the gestational age of 25-34 (61%). The diagnosis of most of the mothers in the study was sever PE (83.9%). None of the mothers had developed a drug-drug interaction. 4(4.6%) patients with renal impairment were being administered MgSO4. There was no record of adverse drug reaction/toxicity developed due to MgSO4. From the total mothers 80 (92%) were found to have appropriate indication for MgSO4. 43(49.4%) of mothers had appropriate dose of MgSO4 as per standard treatment guideline (STG). 81(93.1%) of them were given MgSO4 with the STG recommended duration (24-48hrs). Urine output, DTR and RR were monitored for 36% of mothers. Full Prescriber’s information was written in 96.5% of the charts.

Conclusion: Indications for MgSO4 administration was found appropriate for almost all the mothers, but doses and monitoring of patients was of a significant gap in patients taking MgSO4 which has gone against STG recommendations. Overall the correct dose of Mgso4 is not recorded in obstetric order sheets.