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Research Article

Epidermal Growth Factor (EGF) is Associated with Memory and Executive Functioning in Progressed Parkinson's Disease

Travis H Turner ^1,2*, Ann-Charlotte Granholm¹, Amy Duppstadt-Delambo¹, Heather Boger¹, Guttalu Kumaraswamy¹ and Vanessa Hinson¹

¹Department of Neurosciences, Medical University of South Carolina, USA

²Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, USA

Corresponding Author:

Travis H. Turner, Ph.D.
Medical University of South Carolina
Movement Disorders Program,Suite 308
Mc Clennan Banks Building, 326 Calhoun Street
Charleston, South Carolina 29425, USA
Tel: +1 619-788-3079
E-mail: turnertr@musc.edu

Received date: September 06, 2014; Accepted date: October 16, 2014; Published date: October 24, 2014

Citation:Turner TH, Granholm AC, Delambo AD, Boger H, Kumaraswam G et al. (2014) Epidermal Growth Factor (EGF) is Associated with Memory and Executive Functioning in Progressed Parkinson’s Disease. J Alzheimers Dis Parkinsonism 4:164. doi: 10.4172/2161-0460.1000164

Copyright: Travis H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Objectives: Epidermal Growth Factor (EGF) is a candidate biomarker for cognitive functioning in Parkinson’s disease (PD). Relationships between EGF and cognition were explored in progressed PD. Methods: EGF levels were obtained from a heterogeneous sample of PD patients referred for clinical neuropsychological evaluation. Correlation and effect size analyses evaluated relationships between EGF and cognitive measures. Results: EGF was associated with measures of executive functioning and memory. Conclusion: EGF corresponds to cognition in progressed PD. Findings are consistent with previous studies, and support further investigation of EGF’s utility as a biomarker for cognitive functioning in PD

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