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Abstract

Human Papillomavirus (HPV) is a major contributor to various cancers, including cervical, anal, and oral cancers. The introduction of HPV vaccines has revolutionized cancer prevention by significantly reducing the incidence of these cancers. However, global adoption of HPV vaccination programs varies widely due to differences in healthcare infrastructure, cultural attitudes, and financial resources. High-income countries have achieved substantial vaccine coverage and observed declines in cancer rates, while middle- and low-income countries face challenges such as high vaccine costs, limited healthcare access, and varying levels of public awareness. This article explores global perspectives on HPV vaccination, examining the progress, challenges, and impact of vaccination programs across different regions. It highlights the need for increased international cooperation to enhance vaccine accessibility and effectiveness, ultimately aiming to reduce the global burden of HPV-related diseases.