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Abstract

Acute kidney injury (AKI) is a serious complication following esophageal cancer surgery, adversely affecting patient
outcomes. This nested case-control study aimed to determine the incidence and identify risk factors for AKI after
esophageal cancer surgery. We retrospectively analyzed data from patients undergoing surgery at a tertiary care
hospital. Cases with postoperative AKI were identified, and controls were randomly selected. Multivariate analysis
identified significant risk factors. Results showed [percentage] of patients developed AKI postoperatively, with
advanced age, comorbidities, prolonged operative time, intraoperative blood loss, and postoperative complications
being significant risk factors. These findings underscore the importance of preventive measures and early intervention
to minimize AKI incidence and improve patient outcomes.

Keywords: Acute kidney injury; esophageal cancer surgery; Risk factors; Incidence; Perioperative complications