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Abstract

Streptococcus pneumoniae, a leading cause of morbidity and mortality among children worldwide, presents significant challenges in hospital settings. This study aimed to investigate the epidemiological profile of pediatric S. pneumoniae isolates in both inpatient and outpatient settings at a children’s hospital. A retrospective analysis was conducted, encompassing demographic characteristics, clinical presentations, antimicrobial susceptibility, serotype distribution, risk factors, and vaccination coverage. The findings provide valuable insights into the burden, clinical characteristics, and antimicrobial resistance patterns of pediatric pneumococcal infections, guiding public health interventions to mitigate their impact. Pneumococcal infections caused by Streptococcus pneumoniae remain a significant cause of morbidity and mortality among pediatric patients globally. Despite advancements in medical care and the availability of vaccines, pneumococcal disease continues to pose challenges, particularly in vulnerable populations such as young children. This article explores the clinical manifestations, epidemiology, challenges, and preventive strategies related to pneumococcal infections in pediatric patients.