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Abstract

Substance Use Disorders (SUDs) are complex conditions that involve repeated, problematic use of substances such as alcohol, drugs, and nicotine, often resulting in significant social, psychological, and physical harm. While environmental factors, such as family, peer pressure, and socio-economic status, have been widely studied in relation to SUDs, genetic factors have gained increasing attention as an influential component in their development. This long-term study aims to explore the genetic underpinnings that contribute to the onset of Substance Use Disorders, considering the interaction between genetic predispositions and environmental influences. Using a cohort of individuals from diverse backgrounds, the study investigates how genetic markers, family history, and heritable traits may predispose individuals to SUDs. It also assesses the longitudinal impact of genetic factors over time, evaluating the likelihood of developing SUDs in individuals with varying genetic predispositions. The findings of this study could offer important insights for preventative measures, early interventions, and tailored therapeutic approaches based on genetic risk factors.