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Mucosal Immune Activation: Mechanisms, Challenges, and Implications for Health and Disease

Pujaa Sharma^*

Department of Immunology, College of Public Health, University of Kentucky, U.S.A

Received Date: Sep 03, 2024 / Published Date: Sep 30, 2024

Citation: Pujaa S (2024) Mucosal Immune Activation: Mechanisms, Challenges,and Implications for Health and Disease. J Mucosal Immunol Res 8: 256.

Copyright: © 2024 Pujaa S. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.

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Mucosal immune activation plays a critical role in maintaining the balance between tolerance and immunity at mucosal surfaces. This complex process involves various cellular and molecular mechanisms that are essential for protecting the host from pathogens while preventing excessive inflammation. Key players in mucosal immunity include epithelial cells, dendritic cells, T lymphocytes, and mucosal-associated lymphoid tissues (MALT). Despite the importance of mucosal immune activation, several challenges persist, including the need for improved understanding of its dysregulation in chronic diseases and the development of targeted therapeutic strategies. This article explores the mechanisms underlying mucosal immune activation, the challenges associated with its dysregulation, and its implications for health and disease. By elucidating these aspects, we aim to provide insights into potential therapeutic interventions and advancements in mucosal immunology.