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Abstract

Mucosal surfaces, lining the digestive, respiratory, and other internal tracts, serve as the first line of defense against invading pathogens, constituting a specialized domain of the immune system known as mucosal immunity. This abstract explores the intricate strategies employed by the immune system in the inner sanctum of the body, focusing on the dynamic interactions and adaptive responses that characterize mucosal mastery. Mucosal immunity, often overlooked in traditional discussions of immune defense, reveals its strategic significance as a localized defense mechanism. The digestive tract, a primary site for mucosal immunity, harbors a diverse array of immune cells, creating a formidable barrier against pathogens. The gut guardians, including mucosal-associated lymphoid tissue (MALT), goblet cells, and Paneth cells, orchestrate a complex defense strategy involving mucus production and antimicrobial peptides.