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Journal of Obesity and Metabolism
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  • Mini Review   
  • J Obes Metab 2024, Vol 7(3): 223
  • DOI: 10.4172/jomb.1000223

Phenylalanine Diet in Infants with PAH Deficiency: Sapropterin Monotherapy Consideration

Sara Maxwell*
Department of Pediatrics, Hacettepe University, Turkey
*Corresponding Author : Sara Maxwell, Department of Pediatrics, Hacettepe University, Turkey, Email: sara.maxwell@gmail.com

Received Date: Jun 01, 2024 / Published Date: Jun 30, 2024

Abstract

This study examines the potential need for a phenylalanine-confined diet in young infants diagnosed with phenylalanine hydroxylase (PAH) deficiency, initially managed with sapropterin monotherapy. Evaluating the efficacy and safety of sapropterin as a standalone treatment, we aim to elucidate whether dietary restrictions are warranted in this population. Through a comprehensive analysis of clinical outcomes and metabolic parameters, including phenylalanine levels, we explore the viability of sapropterin monotherapy as an alternative or adjunct to dietary interventions in managing PAH deficiency during infancy. This investigation sheds light on optimizing therapeutic strategies for this vulnerable patient group.

Citation: Sara M (2024) Phenylalanine Diet in Infants with PAH Deficiency:Sapropterin Monotherapy Consideration. J Obes Metab 7: 223. Doi: 10.4172/jomb.1000223

Copyright: © 2024 Sara M. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.

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