Propranolol application in gynecological disease: review
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Abstract
Propranolol is β-adrenergic receptor blocker with reported antioxidant effect and anti-inflammatory action , is used in treatment of the hypertension mainly, and main benefit in treatment patients with angina pectoris or myocardial infarction, add to role in central nervous system diseases as migraines and anxiety disorders, and tremor but rarely used in gynecology field in spite of many action either by beta receptor block or other mechanisms it acts with, such as anti _inflammatory, anticancer, antioxidant activity,pro_poptosis, and wound healing,
In this review, we have discussed the various aspects of propranolol that can be applied in clinical gynecology in number of ways such as local contraceptive, in the treatment of Vulovaginitis by affected main criteria of Trichomonas and Guardia lamblia ,which is motility ,propranolol inhibited motility of both organism and consequence inhibition of the growth of both organism, for the treatment of genital hemangioma,We have also shed some light on experimental studies _ such as its effect on polycystic ovary and endometriosis
Introduction:
Propranolol is a drug with beta blocker effect and used clinical in treated hypertension Thyrotoxicosis, and recent in capillary hemangiomas, anxiety, and essential tremors.(1) but clinical applications in gynecology is limited and route of administration oral route, injection but what about vagina route is used only as spermicidal effect
