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Abstract

Background: Atherosclerosis is a major burden of modern society; ischemic heart disease and cerebrovascular stroke are the top leading causes of death worldwide. There is increase in the number of diabetics in the coming years. Microbiota is linked to development of type 2 DM in numerous ways; increased energy harvest, insulin resistance, chronic low-grade inflammation and modulation of gut-derived peptide secretion. There are accumulating studies that revealed that type 2 diabetic patients showed an altered intestinal microbiota. Aim of the work: To study the association of gut Lactobacillus acidophilus and the presence of atherosclerosis in type 2 diabetic patients.

Keywords: Type 2 diabetes, Intestinal microbiota, Insulin resistance, Atherosclerosis