Role of Surgery in Ovarian Cancer Prevention
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Abstract
Women identified as carrying the BRCA1 or BRCA2 mutation are at high risk for developing ovarian cancer as well as breast cancer. The lifetime risk of developing ovarian cancer for a woman with a BRCA1 mutation is approximately 30% to 60%, although some estimates are as high as 85%. Patients with BRCA2 mutations have an estimated lifetime ovarian cancer risk of approximately 10% to 20%. The optimal management strategy for a woman with an inherited.
susceptibility to ovarian cancer is unclear.
