Selective Synthesis of Some New Carbohydrate Derivatives: Antimicrobial Screening Studies against Human and Phytopathogens
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Abstract
Methyl 4,6-O-benzylidene-α-D-glucopyranoside was specifically changed over to methyl 4,6-O-benzylidene-2-O-(2,6- dichlorobenzoyl)- α-D-glucopyranoside by response with 2,6-dichlorobenzoyl chloride utilizing direct strategy in great yield. Utilizing a wide assortment of acylating specialists, a progression of 3-O-acyl subordinates of this 2-replacement item were additionally arranged. These blended subsidiaries were screened for in vitro antimicrobial action against ten human pathogenic microbes and three parasitic phytopathogens. The investigation uncovered that the acylated subordinates show promising antibacterial and antifungal exercises. The acylated subordinates were discovered to be more successful against the contagious strains than those of the bacterial microorganisms. In any case, a decent number of methyl 4,6-O-benzylidene-α-D-glucopyranoside subordinates showed better antimicrobial movement than the standard anti-microbials.
