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Abstract

Skin toxicology is a multidisciplinary field encompassing the study of adverse effects on the skin resulting from exposure to various chemical, physical, and biological agents. Understanding skin toxicology is crucial for assessing the safety of consumer products, occupational hazards, environmental pollutants, and pharmaceuticals. This review aims to provide an overview of skin toxicology, including its mechanisms, methods of assessment, and implications for human health and safety. Key topics discussed include skin barrier function, mechanisms of toxicity, in vitro and in vivo testing methods, regulatory considerations, and emerging trends in skin toxicology research. By elucidating the complexities of skin toxicology, this review aims to enhance awareness and promote strategies for mitigating risks associated with skin exposure to hazardous substances.