Stem Cell Mobilization and Haploidentical Transplantation for Treating Relapsed Neuroblastoma
*Corresponding Author:Received Date: Nov 01, 2024 / Published Date: Nov 30, 2024
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Abstract
This study investigates the application of haploidentical stem cell transplantation (HSCT) combined with stem cell mobilization as a treatment strategy for relapsed neuroblastoma. Neuroblastoma, a pediatric cancer, poses significant challenges when it recurs, necessitating alternative therapeutic approaches. The research examines the process of stem cell mobilization, including the use of growth factors and chemotherapy to enhance stem cell harvest, and the subsequent role of haploidentical transplantation in re-establishing hematopoietic function. Key considerations such as donor selection, graft-versus-tumor effects, and post-transplantation management are explored. By evaluating clinical outcomes, including survival rates and relapse prevention, the study aims to shed light on the effectiveness and potential of HSCT in improving prognosis for children with relapsed neuroblastoma.
