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Abstract

Trigeminal Neuralgia (TN) is a debilitating neurological condition characterized by excruciating facial pain episodes, often described as electric shocks or stabbing sensations. These paroxysms of agony can profoundly impact individuals' quality of life, leading to significant physical and emotional distress. This clinical guide embarks on a comprehensive journey into the intricate landscape of TN, aiming to unravel its enigmatic pathophysiology, delineate effective diagnostic modalities, and explore the myriad management strategies available. From the intricate interplay of neurovascular conflicts to the discerning nuances of clinical diagnosis, this guide endeavours to provide a thorough understanding of TN. Furthermore, it delves into the diverse therapeutic approaches, ranging from pharmacological interventions to surgical procedures like Microvascular Decompression (MVD) and percutaneous rhizotomy, aiming to alleviate suffering and restore functional well-being. By navigating through the labyrinthine complexities of TN, this guide aspires to equip clinicians and researchers with the insights necessary to confront this formidable challenge head-on. Keywords: Trigeminal neuralgia, Facial pain, Diagnosis, Management, Pathophysiology, Neurovascular conflict, Imaging modalities, Pharmacotherapy, Surgical interventions, Microvascular decompression, Percutaneous rhizotomy, Neurological disorders, Pain management.