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Abstract

Gum disease, or periodontal disease, is a prevalent chronic inflammatory condition affecting the tissues surrounding the teeth. Beyond its well-known impact on oral health, recent research has illuminated significant connections between periodontal disease and various systemic conditions. This article reviews the mechanisms by which periodontal disease may influence systemic health, including bacterial translocation, inflammatory mediator releasae, and immune system dysregulation. Key systemic conditions linked to periodontal disease include cardiovascular disease, diabetes mellitus, respiratory diseases, and adverse pregnancy outcomes. Understanding these connections highlights the importance of maintaining oral hygiene and fostering collaboration between dental and medical professionals to manage and prevent broader health issues. Further research is essential to elucidate these mechanisms and develop effective preventive and therapeutic strategies.