The Effect of Oral Supplementation of Vitamin D3 on Serum Levels of Vitamin D: A Review
Received Date: Dec 29, 2013 / Accepted Date: Feb 10, 2014 / Published Date: Feb 12, 2014
Abstract
Due to the strong interest in the role of vitamin D in health, we tried to find data to illustrate the relationship between oral supplementation and change in serum levels of vitamin D. We reviewed the literature of randomized, placebo-controlled trials of oral supplementation and serum levels of vitamin D through 2014. We found 25 informative studies which showed a significant dose-response between oral supplementation and serum levels of vitamin D with an r2 of 0.61.These data are consistent with single studies and meta-analyses.In conclusion, the data show a consistent relationship that appears to be independent of multiple confounders.
Keywords: Ultraviolet radiation; Cholecalciferol; Serum levels
Citation: Jarrett F, Ducasa GM, Buller DB, Berwick M (2014) The Effect of Oral Supplementation of Vitamin D3 on Serum Levels of Vitamin D: A Review. Epidemiol 4:148. Doi: 10.4172/2161-1165.1000148
Copyright: © 2014 Jarrett F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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