Research Article
THE EFFECT OF TITANIUM DIOXIDE NANOPARTICLES ON SALIVARY ALKALINE PHOSPHATASE ACTIVITY
Abstract
The structural and optical properties of the titanium dioxide nanoparticles (TiO2NPs) have been investigated using (UV-Vis) spectrophotometer and SEM. The produced nanoparticles show small and about sharp round peaks around 220nm. The produced nanoparticles have a spherical shape with an average particle size 脙聝芒聙鹿脙聜芒聙職50 nm. The effect of titanium dioxide NPs was studied on the activity of Alkaline Phosphatase (ALP) in the saliva of 25 patients with gingivitis in comparison to 20 healthy subjects with the average age about 22-23 years for both groups. The results correlated with the observation that salivary alkaline phosphatase activity increase in patient with gingivitis in comparison to control group and salivary ALP activity inhibited by titanium dioxide nanoparticles.
